By Frederick W. Alt
Advances in Immunology, a usual and hugely revered ebook, provides present advancements in addition to entire experiences in immunology. Articles deal with the wide variety of issues that include immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and scientific modalities. Edited and authored through the major scientists within the box, every one quantity offers up to date details and instructions for the future.
* Contributions from prime experts * Informs and updates on all of the newest advancements within the box
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Extra info for Advances in Immunology, Volume 121
Aarts, L. , Erkeland, S. , & Touw, I. P. (2007). Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor. EMBO Journal, 26, 1782–1793. , & Lindenmann, J. (1957). Virus interference. I. The interferon. Proceedings of the Royal Society of London B: Biological Sciences, 147, 258–267. , et al. (2009). Distinct structural requirements for interleukin-4 (IL-4) and IL-13 binding to the shared IL-13 receptor facilitate cellular tuning of cytokine responsiveness. Journal of Biological Chemistry, 284, 24289–24296.
2003). The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: Insights into the mechanisms responsible for improved affinity. Journal of Molecular Biology, 332, 195–204. , & Zhou, H. X. (2011). Rationalizing 5000-fold differences in receptorbinding rate constants of four cytokines. Biophysical Journal, 101, 1175–1183. , et al. (1999). Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity.
F. (1990). Haemopoietic receptors and helical cytokines. Immunology Today, 11, 350–354. , et al. (2010). Covering a broad dynamic range: Information processing at the erythropoietin receptor. Science, 328, 1404–1408. , Ullmann, G. , Smith, J. , & Klingmuller, U. (2008). Packing density of the erythropoietin receptor transmembrane domain correlates with amplification of biological responses. Biochemistry, 47, 11771–11782. Berndt, W. , Chang, D. , Smith, K. , & Ciardelli, T. L. (1994). Mutagenic analysis of a receptor contact site on interleukin-2: Preparation of an IL-2 analog with increased potency.